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Percentile Based Winsorizing 1.0

Company: Golden Helix
Date Added: October 17, 2013  |  Visits: 234

Percentile Based Winsorizing

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This script calculates thresholds for the top and bottom percentiles of log ratio data, as specified by the user, for the purpose of winsorizing * replacing extreme log ratio values with the calculated thresholds. Winsorizing data prevents segmentation algorithms from being driven by outlier values and results in a more accurate determination of regions of copy number variation.<br /><br />For autosomes, the median threshold is used to winsorize the data. Values less than the lower threshold are replaced with the lower threshold, and values that are greater than the upper threshold are replaced with the upper threshold. For non-autosomes, the thresholds for each chromosome are used.

Requirements: No special requirements
Platforms: Mac, Mac OSX
Keyword: Accurate Autosomes Chromosome Determination Greater Lower Median Nonautosomes Number Ratio Regions Replaced Results Threshold Thresholds Upper Values Variationfor Winsorize
Users rating: 0/10

License: Freeware Size: 10.24 KB
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