Percentile Based Winsorizing 1.0

Company: Golden Helix

Date Added: October 17, 2013 | Visits: 404

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This script calculates thresholds for the top and bottom percentiles of log ratio data, as specified by the user, for the purpose of winsorizing * replacing extreme log ratio values with the calculated thresholds. Winsorizing data prevents segmentation algorithms from being driven by outlier values and results in a more accurate determination of regions of copy number variation.<br /><br />For autosomes, the median threshold is used to winsorize the data. Values less than the lower threshold are replaced with the lower threshold, and values that are greater than the upper threshold are replaced with the upper threshold. For non-autosomes, the thresholds for each chromosome are used.

Requirements: No special requirements

Platforms: Mac, Mac OSX

Keyword: Accurate, Autosomes, Chromosome, Determination, Greater, Lower, Median, Nonautosomes, Number, Ratio, Regions, Replaced, Results, Threshold, Thresholds, Upper, Values, Variationfor, Winsorize

Users rating: 0/10

License: Freeware

Size: 10.24 KB

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